The shooting occurred during an argument between two men Wednesday night, according to Capt. David Carlisle of the university's department of public safety.
Officials lifted a campus lockdown after a few hours.
One of the men arguing was critically wounded and three other people suffered non-life-threatening injuries, according to Capt. David Carlisle of the university's department of public safety. The injured were taken to area hospitals.
At first, the campus said one suspect had been arrested. But Carlisle later said two people were in custody.
Authorities say the shooting victims are not affiliated with the campus.